Glutathione

A range of conditions involve depletion of endogenous levels of glutathione due to high oxidative stress, systemic inflammation, or immune dysregulation. Examples include: • Alzheimer’s Disease and Parkinson’s Disease • Cardiovascular Disease • Chronic Fatigue Syndrome • COPD and Asthma • Depression and anxiety disorders • Diabetes • Inflammatory Bowel Disease • Liver Disease/Liver Detoxification of Harmful Chemicals • Multiple Sclerosis • Neuropathy • Rheumatoid Arthritis • Schizophrenia/Bipolar Disorders

Glutathione plays an independent role in liver detoxification by aiding the elimination of harmful substances.

• Individuals with prior kidney disease should avoid high doses of glutathione. • Avoid use in pregnant or breastfeeding individuals due to a lack of safety data. • Excessive glutathione supplementation may impair immune signaling. • Glutathione may have a minimal effect for patients already on anti-inflammatory medications.